Saturday, June 29, 2013
Friday, June 28, 2013
Thursday, June 27, 2013
Scientists
decode the genome of a 700,000 year old horse, breaking the record for
oldest genome sequenced and increasing our understanding of horse
evolution.
The prehistoric equine DNA came from a 15 cm (6
inch) long leg bone, partly preserved by the freezing temperatures of
the Yukon Territory, Western Canada, where it was found. Though the bone
was degraded and host to several other organisms like
bacteria, advanced techniques and computer software enabled the team to
extract, prepare and sequence the ancient horse DNA in unprecedented
detail.
The genome was compared with the genomes of other
members of the horse family, including zebras, donkeys and wild Asian
horses. These results revealed that the ancestor of the Equus genus (the
genus all living horses belong to) branched off from other lineages
4-4.5 million years ago.
The DNA samples also revealed that a
Mongolian equine, Przewalski’s horse, is the last living breed of wild
horse. This endangered species is an offshoot of the domestic horse
lineage and diverged about 50,000 years ago. The team were also able to
tell that horse population size fluctuated with the climate and that
olfaction and a strong immune system have continually been selected for.
What does this mean for reading the genomes of other extinct
animals? Though the limit's been pushed back, time elapsed is still a
very important factor. The conditions the remains were buried in are
also critical - permafrost preserves DNA far better than tropical
conditions do. In addition, DNA previously thought too small or decayed
to be usable could still be sequenced. If we're lucky, the genomes of
our ancestors may not be as out of reach as we thought.
Photo: Przewalski’s horse (Equus ferus przewalskii). Credit to Michael Nichols, National Geographic.
http://www.nature.com/news/ first-horses-arose-4-million-ye ars-ago-1.13261
http://www.wired.com/ wiredscience/2013/06/ ancient-horse-genome/
http:// news.nationalgeographic.com/ news/2013/06/ 130626-ancient-dna-oldest-seque nced-horse-paleontology-scienc e/
http:// blogs.scientificamerican.com/ observations/2013/06/26/ horse-fossil-yields-astonishing ly-old-genomeare-similarly-anc ient-human-genomes-next/
Scientists
decode the genome of a 700,000 year old horse, breaking the record for
oldest genome sequenced and increasing our understanding of horse
evolution.
The prehistoric equine DNA came from a 15 cm (6 inch) long leg bone, partly preserved by the freezing temperatures of the Yukon Territory, Western Canada, where it was found. Though the bone was degraded and host to several other organisms like bacteria, advanced techniques and computer software enabled the team to extract, prepare and sequence the ancient horse DNA in unprecedented detail.
The genome was compared with the genomes of other members of the horse family, including zebras, donkeys and wild Asian horses. These results revealed that the ancestor of the Equus genus (the genus all living horses belong to) branched off from other lineages 4-4.5 million years ago.
The DNA samples also revealed that a Mongolian equine, Przewalski’s horse, is the last living breed of wild horse. This endangered species is an offshoot of the domestic horse lineage and diverged about 50,000 years ago. The team were also able to tell that horse population size fluctuated with the climate and that olfaction and a strong immune system have continually been selected for.
What does this mean for reading the genomes of other extinct animals? Though the limit's been pushed back, time elapsed is still a very important factor. The conditions the remains were buried in are also critical - permafrost preserves DNA far better than tropical conditions do. In addition, DNA previously thought too small or decayed to be usable could still be sequenced. If we're lucky, the genomes of our ancestors may not be as out of reach as we thought.
Photo: Przewalski’s horse (Equus ferus przewalskii). Credit to Michael Nichols, National Geographic.
http://www.nature.com/news/ first-horses-arose-4-million-ye ars-ago-1.13261
http://www.wired.com/ wiredscience/2013/06/ ancient-horse-genome/
http:// news.nationalgeographic.com/ news/2013/06/ 130626-ancient-dna-oldest-seque nced-horse-paleontology-scienc e/
http:// blogs.scientificamerican.com/ observations/2013/06/26/ horse-fossil-yields-astonishing ly-old-genomeare-similarly-anc ient-human-genomes-next/
The prehistoric equine DNA came from a 15 cm (6 inch) long leg bone, partly preserved by the freezing temperatures of the Yukon Territory, Western Canada, where it was found. Though the bone was degraded and host to several other organisms like bacteria, advanced techniques and computer software enabled the team to extract, prepare and sequence the ancient horse DNA in unprecedented detail.
The genome was compared with the genomes of other members of the horse family, including zebras, donkeys and wild Asian horses. These results revealed that the ancestor of the Equus genus (the genus all living horses belong to) branched off from other lineages 4-4.5 million years ago.
The DNA samples also revealed that a Mongolian equine, Przewalski’s horse, is the last living breed of wild horse. This endangered species is an offshoot of the domestic horse lineage and diverged about 50,000 years ago. The team were also able to tell that horse population size fluctuated with the climate and that olfaction and a strong immune system have continually been selected for.
What does this mean for reading the genomes of other extinct animals? Though the limit's been pushed back, time elapsed is still a very important factor. The conditions the remains were buried in are also critical - permafrost preserves DNA far better than tropical conditions do. In addition, DNA previously thought too small or decayed to be usable could still be sequenced. If we're lucky, the genomes of our ancestors may not be as out of reach as we thought.
Photo: Przewalski’s horse (Equus ferus przewalskii). Credit to Michael Nichols, National Geographic.
http://www.nature.com/news/
http://www.wired.com/
http://
http://
Unfortunately,
the chemical treatment is expensive so it will not be used in clean-up
efforts in the near future. It is likely to see more immediate use in
industrial applications.
More info: http://bit.ly/124j9PR
Photo from Ind. Eng. Chem. Res.
More info: http://bit.ly/124j9PR
Photo from Ind. Eng. Chem. Res.
I
have no idea how anyone found this out, but it's completely true. You
don't even necessarily need to have a red light. Apparently, the brain
is addicted to sensation. So when all sensation is blocked out, the
brain creates its own!
A few more tricks to play on your own brain here: http://bit.ly/1agKeaH
A few more tricks to play on your own brain here: http://bit.ly/1agKeaH
Natural Selection
Barryl
Natural Selection is part of the Biological Evolution process. Genetic permutations caused by chance,climatic and catastrophic factors, etc., determine the quality of the offspring ( and may be variations of it, such as mutations, which may result in new species) of/from an organism. Natural selection determines what stays and continue to pro-create = successful adaptation of the organism to the environment at the time of prevailing conditions in the biosphere). As biospheric conditions are not constant over very long periods, means that organisms may be severely stressed to adapt (selection) or die (become extinct). Catastrophic phenomena are part of Nature and so is human intervention - good and bad.
Barryl
Natural Selection is part of the Biological Evolution process. Genetic permutations caused by chance,climatic and catastrophic factors, etc., determine the quality of the offspring ( and may be variations of it, such as mutations, which may result in new species) of/from an organism. Natural selection determines what stays and continue to pro-create = successful adaptation of the organism to the environment at the time of prevailing conditions in the biosphere). As biospheric conditions are not constant over very long periods, means that organisms may be severely stressed to adapt (selection) or die (become extinct). Catastrophic phenomena are part of Nature and so is human intervention - good and bad.
Poor
male dark fishing spiders. The very act of mating sends them into a
comatose state, following which they're eaten by the female. Losing your
virginity is a death sentence.
To copulate with a female, a
male dark fishing spider (Dolomedes tenebrosus) coats his pedipalps (the
two "legs" closest to his face, left) in sperm and inserts one into the
female and inflates a bulb within. During this process
his legs curl up under him and he becomes immobile. Two hours later, he
dies - if the female hasn't already liquified and eaten him.
Though it sounds counter-productive, being eaten can actually increase a
male's chance of fathering offspring. In other spider species, it's
known that a sated female will produce healthier offspring and is less
likely to mate with another male.
These events happen when the
male gets to mate, but sometimes he won't even get that far. If a male
doesn't follow the foreplay rules, the larger female will eat him. If he
accidentally inflates one of his pedipalp bulbs, immobility and death
follow. Once inflated the bulb can't be deflated, and the researchers
believe it is this genital mutilation that results in the male's death
(rather than any act of the female, as noted in other species).
A separate experiment revealed that males have preference for virgin
females. If exposed to the silk of virgin and non-virgin females, the
male will spend more time looking for the virgin female. If mating's
going to cost them their life, they may as well try and make sure they
weren't mating with a female who'd already fertilized her eggs.
To read the paper: http://bit.ly/17CwA1C
Photo credit: Rob Swatski/Flickr/CC BY-NC 2.0.
http://www.wired.co.uk/news/ archive/2013-06/20/spider-sex
http://phys.org/news/ 2013-06-male-dark-fishing-spide rs-die.html
Poor
male dark fishing spiders. The very act of mating sends them into a
comatose state, following which they're eaten by the female. Losing your
virginity is a death sentence.
To copulate with a female, a male dark fishing spider (Dolomedes tenebrosus) coats his pedipalps (the two "legs" closest to his face, left) in sperm and inserts one into the female and inflates a bulb within. During this process his legs curl up under him and he becomes immobile. Two hours later, he dies - if the female hasn't already liquified and eaten him.
Though it sounds counter-productive, being eaten can actually increase a male's chance of fathering offspring. In other spider species, it's known that a sated female will produce healthier offspring and is less likely to mate with another male.
These events happen when the male gets to mate, but sometimes he won't even get that far. If a male doesn't follow the foreplay rules, the larger female will eat him. If he accidentally inflates one of his pedipalp bulbs, immobility and death follow. Once inflated the bulb can't be deflated, and the researchers believe it is this genital mutilation that results in the male's death (rather than any act of the female, as noted in other species).
A separate experiment revealed that males have preference for virgin females. If exposed to the silk of virgin and non-virgin females, the male will spend more time looking for the virgin female. If mating's going to cost them their life, they may as well try and make sure they weren't mating with a female who'd already fertilized her eggs.
To read the paper: http://bit.ly/17CwA1C
Photo credit: Rob Swatski/Flickr/CC BY-NC 2.0.
http://www.wired.co.uk/news/ archive/2013-06/20/spider-sex
http://phys.org/news/ 2013-06-male-dark-fishing-spide rs-die.html
To copulate with a female, a male dark fishing spider (Dolomedes tenebrosus) coats his pedipalps (the two "legs" closest to his face, left) in sperm and inserts one into the female and inflates a bulb within. During this process his legs curl up under him and he becomes immobile. Two hours later, he dies - if the female hasn't already liquified and eaten him.
Though it sounds counter-productive, being eaten can actually increase a male's chance of fathering offspring. In other spider species, it's known that a sated female will produce healthier offspring and is less likely to mate with another male.
These events happen when the male gets to mate, but sometimes he won't even get that far. If a male doesn't follow the foreplay rules, the larger female will eat him. If he accidentally inflates one of his pedipalp bulbs, immobility and death follow. Once inflated the bulb can't be deflated, and the researchers believe it is this genital mutilation that results in the male's death (rather than any act of the female, as noted in other species).
A separate experiment revealed that males have preference for virgin females. If exposed to the silk of virgin and non-virgin females, the male will spend more time looking for the virgin female. If mating's going to cost them their life, they may as well try and make sure they weren't mating with a female who'd already fertilized her eggs.
To read the paper: http://bit.ly/17CwA1C
Photo credit: Rob Swatski/Flickr/CC BY-NC 2.0.
http://www.wired.co.uk/news/
http://phys.org/news/
Tuesday, June 25, 2013
Monday, June 24, 2013
Unlike
most multicellular organisms, bacteria reproduce asexually - meaning
that no genetic material is exchanged during reproduction. Instead,
they're capable of gene transfer, where one bacterial cell will insert
some of their genetic material into another. This method of gene
transfer is often responsible for bacterial populations rapid evolution.
Now, a study has found that some bacteria are capable of inserting
their genetic materia into human genomes - and interestingly, it was
found to be more common in cancerous cells.
More information: http://bit.ly/132z5Zf
Now, a study has found that some bacteria are capable of inserting their genetic materia into human genomes - and interestingly, it was found to be more common in cancerous cells.
More information: http://bit.ly/132z5Zf
Sunday, June 23, 2013
Rhino
are poached in the hundreds every year. One of the main reasons for
this the Asian medicine industry. Rhino horns are believed to be miracle
cures for everything from cancer to erectile dysfunction. (In reality,
there is no evidence that rhino horn helps at all. They are composed of
keratin, the same stuff as your fingernails.) The huge demand for the
horns causes the above-mentioned poaching.
South Africa in particular has been hit hard by poaching. It has more
rhino* than many other countries in Africa. Although they are more
successful in breeding, the South African rhino are targeted by
poachers. More often than not, the rhino are killed or seriously injured
as their horns are chopped off and they are left to die.
A
group of vets has taken up the challenge of trying to rescue the few
rhino that survive the ordeal. Although many of these vets do this
voluntarily, the cost of their efforts is extremely high. Dr William
Fowlds, South Africa’s leading rhino vet is actively involved in such
efforts. He assists other vets in South Africa with managing rhino that
survive poaching attacks. In his words "This year alone South Africa has
lost more than 2.5 rhino per day. Most of the poaching occurs in the
northern Kruger National Park, a park the size of Israel... Trained
rangers put their lives at risk, for very little salary.”
Dr
Fowlds is assisted by veterinary pathologist Prof Fred Reyers from the
University of Lincoln in the UK. He analyses the blood-work of the
injured rhino in order to aid the vets treating them. He says that when
rhino are shot with rifles, they are severely stunned, which allows
poachers to remove the horn from the rhino. The injuries that they
sustain from getting shot can often result in infection. Furthermore, if
the injured rhino falls onto its side, the sheer mass of the animal
cuts off blood flow from the lower side of its body, causing muscle
death. Poachers are also known to use tranquiliser dart guns to
immobilize the rhino. Most of the time, an antidote is not administered.
The injuries from the bullet wounds, the lesions from the removal of
the horn and the degradation of the muscles in the rhino all contribute
to sepsis developing in the rhino. This results in internal damage to
vital organs like the kidneys and lungs. As such, it is impossible to
accurately gauge the seriousness of the injury from an external
perspective. So, Prof Reyers analyses blood-work to get a clear idea of
the severity of the rhinos’ condition so that the on-site vets can
adjust their treatments accordingly.
As Dr Fowlds says, “These
living dinosaurs are truly iconic symbols of our successes and failures
as custodians of this planet. The current rhino situation is a dying
testimony of our conservation efforts."
*Yes, the plural of ‘Rhino’ is ‘Rhino’…
Read all about it: http://bit.ly/1c6cmtu
Image URL: http://bit.ly/184hrT7
South Africa in particular has been hit hard by poaching. It has more rhino* than many other countries in Africa. Although they are more successful in breeding, the South African rhino are targeted by poachers. More often than not, the rhino are killed or seriously injured as their horns are chopped off and they are left to die.
A group of vets has taken up the challenge of trying to rescue the few rhino that survive the ordeal. Although many of these vets do this voluntarily, the cost of their efforts is extremely high. Dr William Fowlds, South Africa’s leading rhino vet is actively involved in such efforts. He assists other vets in South Africa with managing rhino that survive poaching attacks. In his words "This year alone South Africa has lost more than 2.5 rhino per day. Most of the poaching occurs in the northern Kruger National Park, a park the size of Israel... Trained rangers put their lives at risk, for very little salary.”
Dr Fowlds is assisted by veterinary pathologist Prof Fred Reyers from the University of Lincoln in the UK. He analyses the blood-work of the injured rhino in order to aid the vets treating them. He says that when rhino are shot with rifles, they are severely stunned, which allows poachers to remove the horn from the rhino. The injuries that they sustain from getting shot can often result in infection. Furthermore, if the injured rhino falls onto its side, the sheer mass of the animal cuts off blood flow from the lower side of its body, causing muscle death. Poachers are also known to use tranquiliser dart guns to immobilize the rhino. Most of the time, an antidote is not administered.
The injuries from the bullet wounds, the lesions from the removal of the horn and the degradation of the muscles in the rhino all contribute to sepsis developing in the rhino. This results in internal damage to vital organs like the kidneys and lungs. As such, it is impossible to accurately gauge the seriousness of the injury from an external perspective. So, Prof Reyers analyses blood-work to get a clear idea of the severity of the rhinos’ condition so that the on-site vets can adjust their treatments accordingly.
As Dr Fowlds says, “These living dinosaurs are truly iconic symbols of our successes and failures as custodians of this planet. The current rhino situation is a dying testimony of our conservation efforts."
*Yes, the plural of ‘Rhino’ is ‘Rhino’…
Read all about it: http://bit.ly/1c6cmtu
Image URL: http://bit.ly/184hrT7
Saturday, June 22, 2013
Bacteria inside bacteria inside bugs, a symbiotic happy family.
Citrus mealybugs (Planococcus citri), which look a bit like white
woodlice, feed on plant sap. However plant sap doesn't provide all the
nutrients they need, which is where the bacteria come into play.
Tremblaya princeps (which lives inside the mealybug) and Moranella
endobia (which lives inside Tremblaya) work symbiotically with the mealybug to provide the nutrients it needs.
Given that Moranella lives inside Tremblaya, you can guess which is
larger. Their genomes, however, go the other way - Tremblaya's is only
120 genes long, and the smallest genome of any bacterium. Moranella's is
almost 4 times as long. Tremblaya is also missing genes essential for
survival, with Moranella picking up the slack for its bacterium host.
How can Tremblaya's genome have become so small? The researchers
wondered if it had transferred them to its mealybug host, but
investigation revealed something even stranger. The mealybug's genome
does contain genes from bacteria, but these aren't from Tremblaya or
Moranella - they're from 3 separate bacteria types, and none of those
three live in the mealybug today.
So really, it's bacteria inside bacteria inside insects, using genes from 3 bacteria species that aren't there.
The international team hope their work will help us understand how
organelles, such as the mitochondria in our cells, came to be. These
started out as symbiotic bacteria before becoming the cell powerhouses
they are for us. The mealybug/Tremblaya/Moranella interactions may be
one pathway bacteria can take to becoming vital parts of cells.
Photo credit: USDA ARS Photo Unit
Further reading and sources:
http://www.sciencedaily.com/ releases/2013/06/ 130620142954.htm
http://www.livescience.com/ 37597-bugs-house-russian-doll-b acteria.html
http:// phenomena.nationalgeographic.co m/2013/06/20/ snug-as-a-bug-in-a-bug-in-a-bug /
Bacteria inside bacteria inside bugs, a symbiotic happy family.
Citrus mealybugs (Planococcus citri), which look a bit like white woodlice, feed on plant sap. However plant sap doesn't provide all the nutrients they need, which is where the bacteria come into play. Tremblaya princeps (which lives inside the mealybug) and Moranella endobia (which lives inside Tremblaya) work symbiotically with the mealybug to provide the nutrients it needs.
Given that Moranella lives inside Tremblaya, you can guess which is larger. Their genomes, however, go the other way - Tremblaya's is only 120 genes long, and the smallest genome of any bacterium. Moranella's is almost 4 times as long. Tremblaya is also missing genes essential for survival, with Moranella picking up the slack for its bacterium host.
How can Tremblaya's genome have become so small? The researchers wondered if it had transferred them to its mealybug host, but investigation revealed something even stranger. The mealybug's genome does contain genes from bacteria, but these aren't from Tremblaya or Moranella - they're from 3 separate bacteria types, and none of those three live in the mealybug today.
So really, it's bacteria inside bacteria inside insects, using genes from 3 bacteria species that aren't there.
The international team hope their work will help us understand how organelles, such as the mitochondria in our cells, came to be. These started out as symbiotic bacteria before becoming the cell powerhouses they are for us. The mealybug/Tremblaya/Moranella interactions may be one pathway bacteria can take to becoming vital parts of cells.
Photo credit: USDA ARS Photo Unit
Further reading and sources:
http://www.sciencedaily.com/ releases/2013/06/ 130620142954.htm
http://www.livescience.com/ 37597-bugs-house-russian-doll-b acteria.html
http:// phenomena.nationalgeographic.co m/2013/06/20/ snug-as-a-bug-in-a-bug-in-a-bug /
Citrus mealybugs (Planococcus citri), which look a bit like white woodlice, feed on plant sap. However plant sap doesn't provide all the nutrients they need, which is where the bacteria come into play. Tremblaya princeps (which lives inside the mealybug) and Moranella endobia (which lives inside Tremblaya) work symbiotically with the mealybug to provide the nutrients it needs.
Given that Moranella lives inside Tremblaya, you can guess which is larger. Their genomes, however, go the other way - Tremblaya's is only 120 genes long, and the smallest genome of any bacterium. Moranella's is almost 4 times as long. Tremblaya is also missing genes essential for survival, with Moranella picking up the slack for its bacterium host.
How can Tremblaya's genome have become so small? The researchers wondered if it had transferred them to its mealybug host, but investigation revealed something even stranger. The mealybug's genome does contain genes from bacteria, but these aren't from Tremblaya or Moranella - they're from 3 separate bacteria types, and none of those three live in the mealybug today.
So really, it's bacteria inside bacteria inside insects, using genes from 3 bacteria species that aren't there.
The international team hope their work will help us understand how organelles, such as the mitochondria in our cells, came to be. These started out as symbiotic bacteria before becoming the cell powerhouses they are for us. The mealybug/Tremblaya/Moranella interactions may be one pathway bacteria can take to becoming vital parts of cells.
Photo credit: USDA ARS Photo Unit
Further reading and sources:
http://www.sciencedaily.com/
http://www.livescience.com/
http://
Friday, June 21, 2013
New research reveals the origin of The Hoff - the Hoff yeti crab, that is.
When these crabs were found in 2011, their hairy chests reminded
researchers of David Hasselhoff. These hairs trap bacteria where it can
be "farmed" until the crab scrapes it off with its comb-like mouthparts
and eats it. The crabs live in the deep sea, more than 2000m down, and
live around hydrothermal vents where they can
feed their bacteria in the mineral-rich vent water. It's a fine line
between being close enough to reach minerals and getting boiled alive in
the 380°C (716 Fahrenheit) water.
It was previously thought
that yeti crabs were "living fossils", but new research shows all four
yeti crab species have a common ancestor around 35-40 million years ago.
DNA analysis suggests the crabs originated around vents in the eastern
Pacific Ocean and migrated west, with larvae hitching rides in
fast-moving ocean currents.
Current vent species can be traced
back around 55 million years to a period of global warming, when the
atmosphere warmed and deep sea oxygen levels dropped. This could have
killed off the vent species of the time and cleared the way for yeti
crabs to move in.
"Yeti crabs and other such creatures may in
fact be especially prone to extinction when there is less oxygen
available in the deep ocean,’ says Dr Nicolai Roterman (of Oxford
University, UK). "This is because if deep-sea ocean oxygen levels fall,
the amount of oxygen available to these animals - which already live in
an oxygen-poor environment at the limits of their physiological
tolerance - may drop below the minimum level at which they can survive.
They would face the stark choice of "suffocate or starve"."
To read the paper: http://bit.ly/14mtvwq
Photo: Close-up of "The Hoff" Yeti crab (credit to David Shale).
Colonies of crabs around heat vents on the East Scotia Ridge in the
Southern Ocean (CHESSO Consortium).
http://www.ox.ac.uk/media/ news_stories/2013/130619.html
http://www.livescience.com/ 37532-yeti-crab-evolution.html
http://www.bbc.co.uk/news/ science-environment-22952728
When these crabs were found in 2011, their hairy chests reminded researchers of David Hasselhoff. These hairs trap bacteria where it can be "farmed" until the crab scrapes it off with its comb-like mouthparts and eats it. The crabs live in the deep sea, more than 2000m down, and live around hydrothermal vents where they can feed their bacteria in the mineral-rich vent water. It's a fine line between being close enough to reach minerals and getting boiled alive in the 380°C (716 Fahrenheit) water.
It was previously thought that yeti crabs were "living fossils", but new research shows all four yeti crab species have a common ancestor around 35-40 million years ago. DNA analysis suggests the crabs originated around vents in the eastern Pacific Ocean and migrated west, with larvae hitching rides in fast-moving ocean currents.
Current vent species can be traced back around 55 million years to a period of global warming, when the atmosphere warmed and deep sea oxygen levels dropped. This could have killed off the vent species of the time and cleared the way for yeti crabs to move in.
"Yeti crabs and other such creatures may in fact be especially prone to extinction when there is less oxygen available in the deep ocean,’ says Dr Nicolai Roterman (of Oxford University, UK). "This is because if deep-sea ocean oxygen levels fall, the amount of oxygen available to these animals - which already live in an oxygen-poor environment at the limits of their physiological tolerance - may drop below the minimum level at which they can survive. They would face the stark choice of "suffocate or starve"."
To read the paper: http://bit.ly/14mtvwq
Photo: Close-up of "The Hoff" Yeti crab (credit to David Shale). Colonies of crabs around heat vents on the East Scotia Ridge in the Southern Ocean (CHESSO Consortium).
http://www.ox.ac.uk/media/
http://www.livescience.com/
http://www.bbc.co.uk/news/
Thursday, June 20, 2013
Evolution
We can only imagine being cancer-proof, but for naked mole rats it's reality. New research is lifting the curtain on how they've attained cancer immunity.
It turns out mole rats can thank a substance named hyaluronan for their immunity. This sugar holds cells and tissues together and makes skin elastic (remember that later). Other animals, including us, posses hyaluronan, but mole rats produce a large amounts of long chains of it (over 5 times bigger than ours). These chains form a cage around cells, preventing potentially cancerous cells from replicating, and also controlling cell growth. Experiments revealed that without hyaluronan, mole rats cells could become cancerous.
It's suggested that naked mole rats have cancer-resistance as a side effect of evolving stretchy skin. Not having fur means that their skin receives a great deal of stress when burrowing - without very stretchy skin and flexible tissue, they could cause themselves injury. This selection pressure gave them more and longer hyaluronan and as a consequence, cancer immunity.
Other mechanisms may be at work as well as hyaluronan. The mole rat's genome has revealed several cancer-related genes that differ between them and other vertebrates. Similarly previous studies have suggested other mechanisms.
"By looking at this completely weird and unusual organism, we can find some novel mechanisms that apply across mammals," said Chris Faulkes (Queen Mary, University of London). "Understanding some of these amazing things could have broad applicability for human health... It's possible that one day some of the cool features of the animals could be engineered into humans. But we may all end up looking like naked mole rats."
Photo credit: Brandon Vick/University of Rochester.
http://www.nature.com/news/simple-molecule-prevents-mole-rats-from-getting-cancer-1.13236
http://www.livescience.com/37555-cancer-resistance-naked-mole-rats.html
http://www.newscientist.com/article/mg21829224.800-naked-mole-rats-reveal-why-they-are-immune-to-cancer.html#.UcMJKfmZO8A
http://phenomena.nationalgeographic.com/2013/06/19/why-naked-mole-rats-dont-get-cancer/
We can only imagine being cancer-proof, but for naked mole rats it's reality. New research is lifting the curtain on how they've attained cancer immunity. It turns out mole rats can thank a substance named hyaluronan for their immunity. This sugar holds cells and tissues together and makes skin elastic (remember that later). Other animals, including us, posses hyaluronan, but mole rats produce a large amounts of long chains of it (over 5 times bigger than ours). These chains form a cage around cells, preventing potentially cancerous cells from replicating, and also controlling cell growth. Experiments revealed that without hyaluronan, mole rats cells could become cancerous. It's suggested that naked mole rats have cancer-resistance as a side effect of evolving stretchy skin. Not having fur means that their skin receives a great deal of stress when burrowing - without very stretchy skin and flexible tissue, they could cause themselves injury. This selection pressure gave them more and longer hyaluronan and as a consequence, cancer immunity. Other mechanisms may be at work as well as hyaluronan. The mole rat's genome has revealed several cancer-related genes that differ between them and other vertebrates. Similarly previous studies have suggested other mechanisms. "By looking at this completely weird and unusual organism, we can find some novel mechanisms that apply across mammals," said Chris Faulkes (Queen Mary, University of London). "Understanding some of these amazing things could have broad applicability for human health... It's possible that one day some of the cool features of the animals could be engineered into humans. But we may all end up looking like naked mole rats." Photo credit: Brandon Vick/University of Rochester. http://www.nature.com/news/simple-molecule-prevents-mole-rats-from-getting-cancer-1.13236 http://www.livescience.com/37555-cancer-resistance-naked-mole-rats.html http://www.newscientist.com/article/mg21829224.800-naked-mole-rats-reveal-why-they-are-immune-to-cancer.html#.UcMJKfmZO8A http://phenomena.nationalgeographic.com/2013/06/19/why-naked-mole-rats-dont-get-cancer/
Tuesday, June 18, 2013
Sunday, June 16, 2013
Ever
wondered how whales can stay underwater for so long? Scientists from
the University of Liverpool might be able to tell you the answer!
Myoglobin is an oxygen-binding protein which gives meat its reddish
colour. In elite diving mammals (such as whales), the concentration of
myoglobin in muscle tissue is so high that the muscle is almost black in
colour. However, at such high concentrations, proteins
tend to aggregate together, which deteriorates their function. Up till
now, not much was known about how mammalian divers overcame this
obstacle.
The researchers took an in-depth (no pun intended)
look at the “electrical charge on the surface of” the myoglobin
molecule. They noticed that mammals that spent longer periods underwater
had a greater amount of electrical charge on the surface of the
myoglobin molecule. This trend even applied to semi aquatic mammals!
This suggests that the electrical charges in the molecules cause them to
repel one another, effectively cancelling out the aggregation problem.
So with higher electrical charge on the molecules, a diving mammal can
afford to have a higher concentration of myoglobin in muscles.
After identifying this molecular signature, the researchers mapped it
out on the mammalian phylogenetic tree. Then, they reconstructed the
muscle oxygen stores, and therefore diving capacity, of extinct
ancestors of modern mammals. This in-turn allows us to understand the
predatory opportunities that existed in ancient aquatic habitats.
From a medical perspective, this research is also important because it
could help us understand diseases such as diabetes and Alzheimer’s,
where the proteins’ clumping together becomes a problem. It can also aid
in the creation of artificial blood substitutes, where protein
aggregation must be taken into account.
Read all about it: http://bit.ly/19w6ayi
Image URL: http://bit.ly/19GJ1EU
Ever
wondered how whales can stay underwater for so long? Scientists from
the University of Liverpool might be able to tell you the answer!
Myoglobin is an oxygen-binding protein which gives meat its reddish colour. In elite diving mammals (such as whales), the concentration of myoglobin in muscle tissue is so high that the muscle is almost black in colour. However, at such high concentrations, proteins tend to aggregate together, which deteriorates their function. Up till now, not much was known about how mammalian divers overcame this obstacle.
The researchers took an in-depth (no pun intended) look at the “electrical charge on the surface of” the myoglobin molecule. They noticed that mammals that spent longer periods underwater had a greater amount of electrical charge on the surface of the myoglobin molecule. This trend even applied to semi aquatic mammals! This suggests that the electrical charges in the molecules cause them to repel one another, effectively cancelling out the aggregation problem. So with higher electrical charge on the molecules, a diving mammal can afford to have a higher concentration of myoglobin in muscles.
After identifying this molecular signature, the researchers mapped it out on the mammalian phylogenetic tree. Then, they reconstructed the muscle oxygen stores, and therefore diving capacity, of extinct ancestors of modern mammals. This in-turn allows us to understand the predatory opportunities that existed in ancient aquatic habitats.
From a medical perspective, this research is also important because it could help us understand diseases such as diabetes and Alzheimer’s, where the proteins’ clumping together becomes a problem. It can also aid in the creation of artificial blood substitutes, where protein aggregation must be taken into account.
Read all about it: http://bit.ly/19w6ayi
Image URL: http://bit.ly/19GJ1EU
Myoglobin is an oxygen-binding protein which gives meat its reddish colour. In elite diving mammals (such as whales), the concentration of myoglobin in muscle tissue is so high that the muscle is almost black in colour. However, at such high concentrations, proteins tend to aggregate together, which deteriorates their function. Up till now, not much was known about how mammalian divers overcame this obstacle.
The researchers took an in-depth (no pun intended) look at the “electrical charge on the surface of” the myoglobin molecule. They noticed that mammals that spent longer periods underwater had a greater amount of electrical charge on the surface of the myoglobin molecule. This trend even applied to semi aquatic mammals! This suggests that the electrical charges in the molecules cause them to repel one another, effectively cancelling out the aggregation problem. So with higher electrical charge on the molecules, a diving mammal can afford to have a higher concentration of myoglobin in muscles.
After identifying this molecular signature, the researchers mapped it out on the mammalian phylogenetic tree. Then, they reconstructed the muscle oxygen stores, and therefore diving capacity, of extinct ancestors of modern mammals. This in-turn allows us to understand the predatory opportunities that existed in ancient aquatic habitats.
From a medical perspective, this research is also important because it could help us understand diseases such as diabetes and Alzheimer’s, where the proteins’ clumping together becomes a problem. It can also aid in the creation of artificial blood substitutes, where protein aggregation must be taken into account.
Read all about it: http://bit.ly/19w6ayi
Image URL: http://bit.ly/19GJ1EU
Thursday, June 13, 2013
Even
though it's the fastest land animal on the planet, it's not actually
speed that's key to a cheetah's hunt. New research reveals cheetahs rely
more on their extreme agility and maneuverability to bring down their
prey.
The speed of cheetahs has been subject to scientific
debate. Measurements taken in the '60s clocked them reaching speeds of
64 mph, but subsequent investigations only measured them
hitting 40 mph (about the speed of a greyhound). These studies were
also carried out with captive cheetahs, meaning they could tell us
little about how cheetahs really used their speed in the wild.
To find out what these cats are really capable of, a team of
researchers tracked the movements of 5 wild cheetahs with collars. These
collars monitored speed, acceleration, deceleration and location and
collected 367 runs over 17 months.
The researchers were
surprised to find out agility and maneuverability were more important
than speed during a hunt. They were capable of very high speeds (one,
called Ferrari, was clocked at 58mph) but the average top speed taken
was 33mph, and even this was only maintained for a few seconds. There
was also very little difference in speed between successful and failed
hunts.
The data revealed, however, that the big cats are
champions at rapid acceleration and deceleration. Cheetahs can speed up
or slow down by 9mph in a single stride. Their muscle power output per
kilogram (100 watts) during acceleration is the highest of any land
animal - for comparison, Usain Bolt can produce 25 watts. Speeding up
and slowly down rapidly are more important in catching prey than simple
speed.
Conventional wisdom also painted cheetahs as dawn
hunters, staying within open grasslands. The new data overturns this:
the cheetahs hunted during during the day too and half the runs occurred
among shrubs, trees and heavy vegetation.
Photo: Cheetah wearing a tracking collar. Credit to Structure & Motion Lab, RVC.
http://www.livescience.com/ 37372-cheetah-running-hunting-b ehavior.html
http:// phenomena.nationalgeographic.co m/2013/06/12/ collars-reveal-why-just-how-ext reme-cheetahs-can-be/
http://news.sciencemag.org/ sciencenow/2013/06/ cheetah-agility-more-important- t.html
http://www.nature.com/news/ speed-test-for-wild-cheetahs-1. 13179
The speed of cheetahs has been subject to scientific debate. Measurements taken in the '60s clocked them reaching speeds of 64 mph, but subsequent investigations only measured them hitting 40 mph (about the speed of a greyhound). These studies were also carried out with captive cheetahs, meaning they could tell us little about how cheetahs really used their speed in the wild.
To find out what these cats are really capable of, a team of researchers tracked the movements of 5 wild cheetahs with collars. These collars monitored speed, acceleration, deceleration and location and collected 367 runs over 17 months.
The researchers were surprised to find out agility and maneuverability were more important than speed during a hunt. They were capable of very high speeds (one, called Ferrari, was clocked at 58mph) but the average top speed taken was 33mph, and even this was only maintained for a few seconds. There was also very little difference in speed between successful and failed hunts.
The data revealed, however, that the big cats are champions at rapid acceleration and deceleration. Cheetahs can speed up or slow down by 9mph in a single stride. Their muscle power output per kilogram (100 watts) during acceleration is the highest of any land animal - for comparison, Usain Bolt can produce 25 watts. Speeding up and slowly down rapidly are more important in catching prey than simple speed.
Conventional wisdom also painted cheetahs as dawn hunters, staying within open grasslands. The new data overturns this: the cheetahs hunted during during the day too and half the runs occurred among shrubs, trees and heavy vegetation.
Photo: Cheetah wearing a tracking collar. Credit to Structure & Motion Lab, RVC.
http://www.livescience.com/
http://
http://news.sciencemag.org/
http://www.nature.com/news/
Wednesday, June 12, 2013
New videos of oarfish in their native habitat reveal more about this strange and elusive fish.
The giant oarfish (Regalecus glesne) is the largest of the bony fish.
They have been recorded at lengths of 8 metres (26 feet), but it's been
suggested they could reach lengths of 15 metres (nearly 50 feet).
Several myths surround oarfish; they've been suggested as the origin of
"sea serpent" legends and are considered a bad omen in Japan.
Currently there is a lot we don't know about oarfish. The specimens
available for study have typically been washed up onto the beach/shallow
water and are either dead or dying. While these specimens can tell us
about oarfish anatomy, they are of little help in studying aspects like
behaviour.
That's one of the reasons these videos, recorded
near the Gulf of Mexico, are so exciting. They offer a rare high-quality
glimpse into the life of an oarfish in its habitat. Five videos were
taken between 2008 and 2011. The videos reveal a lot about oarfish -
they can be found nearly 500 metres deep (over 1,600 feet) and can hang
almost vertically in the water. Undulation of their long dorsal fin
allows them precise control of movement, but they can also undulate
their whole body when they require speed.
The highest-quality
video revealed the oarfish had company. Clinging to its dorsal spine was
a parasitic isopod (imagine a giant underwater pillbug/woodlouse).
Given that the oarfish did not immediately flee the ROV (sticking around
for nearly 10 minutes), the team believe it has few natural predators.
See one of the videos here (good stuff starts nearly 5 minutes in): http://www.youtube.com/ watch?v=-yIWfCAC5y0
Image: Still from one of the videos. Credit to Mark Benfield/Journal of Fish Biology.
http://www.livescience.com/ 37327-video-deep-sea-oarfish.ht ml
http://news.discovery.com/ earth/oceans/ rare-sea-serpent-caught-on-vide o-130610.htm
http:// newswatch.nationalgeographic.co m/2013/06/11/ rare-video-of-giant-sea-serpent -oarfish-caught/
http://deepseanews.com/2013/ 06/ video-of-an-oarfish-in-the-wild /
The giant oarfish (Regalecus glesne) is the largest of the bony fish. They have been recorded at lengths of 8 metres (26 feet), but it's been suggested they could reach lengths of 15 metres (nearly 50 feet). Several myths surround oarfish; they've been suggested as the origin of "sea serpent" legends and are considered a bad omen in Japan.
Currently there is a lot we don't know about oarfish. The specimens available for study have typically been washed up onto the beach/shallow water and are either dead or dying. While these specimens can tell us about oarfish anatomy, they are of little help in studying aspects like behaviour.
That's one of the reasons these videos, recorded near the Gulf of Mexico, are so exciting. They offer a rare high-quality glimpse into the life of an oarfish in its habitat. Five videos were taken between 2008 and 2011. The videos reveal a lot about oarfish - they can be found nearly 500 metres deep (over 1,600 feet) and can hang almost vertically in the water. Undulation of their long dorsal fin allows them precise control of movement, but they can also undulate their whole body when they require speed.
The highest-quality video revealed the oarfish had company. Clinging to its dorsal spine was a parasitic isopod (imagine a giant underwater pillbug/woodlouse). Given that the oarfish did not immediately flee the ROV (sticking around for nearly 10 minutes), the team believe it has few natural predators.
See one of the videos here (good stuff starts nearly 5 minutes in): http://www.youtube.com/
Image: Still from one of the videos. Credit to Mark Benfield/Journal of Fish Biology.
http://www.livescience.com/
http://news.discovery.com/
http://
http://deepseanews.com/2013/
Tuesday, June 11, 2013
Male lyrebirds perform specific dance moves to their songs to attract females.
Lyrebirds, found in Australia, are renowned for their voices. They are
fantastic mimics, combining their own sounds with those of the forest
(even sounds that naturally wouldn't be there, such as chainsaws and
camera shutters). New research has found that superb lyrebirds (Menura
novaehollandiae) have particular choreography for certain songs.
Songs are not always accompanied by dances - males only show off their
moves to four song types, and each has a different dance. Lyrebirds
sometimes mess up and perform the wrong move, a sign that combining
singing and dancing could be challenging for them. Moves include
behaviours such as hopping, flapping their wings, and fanning and
contracting their lyre-shaped tails.
It's been suggested males
learn their dances while they are growing up. Males often perform in
groups, providing juveniles a chance to learn from adults, and maturity
comes at around 7 years of age - likely sufficient time for them to
learn how to dance. It's also not known what exactly the females are
looking for, or whether moves vary over time and between populations.
It's also possible that birds of paradise and manakins have similar
dancing skills, but so far no one carried out a study like this with
them.
To see the video: http://www.eurekalert.org/ multimedia/pub/ 57148.php?from=241018
To read the paper: http://bit.ly/1bsaOKc
Photo credit: Alex Maisey.
http://www.eurekalert.org/ pub_releases/2013-06/ cp-slm053013.php
http://www.newscientist.com/ article/ dn23659-zoologger-the-lyrebird- thats-a-songanddance-man.html
http://www.wired.com/ wiredscience/2013/06/ superb-lyrebird-dance-moves/
http://www.livescience.com/ 37219-lyrebirds-sing-and-dance. html
Male lyrebirds perform specific dance moves to their songs to attract females.
Lyrebirds, found in Australia, are renowned for their voices. They are fantastic mimics, combining their own sounds with those of the forest (even sounds that naturally wouldn't be there, such as chainsaws and camera shutters). New research has found that superb lyrebirds (Menura novaehollandiae) have particular choreography for certain songs.
Songs are not always accompanied by dances - males only show off their moves to four song types, and each has a different dance. Lyrebirds sometimes mess up and perform the wrong move, a sign that combining singing and dancing could be challenging for them. Moves include behaviours such as hopping, flapping their wings, and fanning and contracting their lyre-shaped tails.
It's been suggested males learn their dances while they are growing up. Males often perform in groups, providing juveniles a chance to learn from adults, and maturity comes at around 7 years of age - likely sufficient time for them to learn how to dance. It's also not known what exactly the females are looking for, or whether moves vary over time and between populations. It's also possible that birds of paradise and manakins have similar dancing skills, but so far no one carried out a study like this with them.
To see the video: http://www.eurekalert.org/ multimedia/pub/ 57148.php?from=241018
To read the paper: http://bit.ly/1bsaOKc
Photo credit: Alex Maisey.
http://www.eurekalert.org/ pub_releases/2013-06/ cp-slm053013.php
http://www.newscientist.com/ article/ dn23659-zoologger-the-lyrebird- thats-a-songanddance-man.html
http://www.wired.com/ wiredscience/2013/06/ superb-lyrebird-dance-moves/
http://www.livescience.com/ 37219-lyrebirds-sing-and-dance. html
Lyrebirds, found in Australia, are renowned for their voices. They are fantastic mimics, combining their own sounds with those of the forest (even sounds that naturally wouldn't be there, such as chainsaws and camera shutters). New research has found that superb lyrebirds (Menura novaehollandiae) have particular choreography for certain songs.
Songs are not always accompanied by dances - males only show off their moves to four song types, and each has a different dance. Lyrebirds sometimes mess up and perform the wrong move, a sign that combining singing and dancing could be challenging for them. Moves include behaviours such as hopping, flapping their wings, and fanning and contracting their lyre-shaped tails.
It's been suggested males learn their dances while they are growing up. Males often perform in groups, providing juveniles a chance to learn from adults, and maturity comes at around 7 years of age - likely sufficient time for them to learn how to dance. It's also not known what exactly the females are looking for, or whether moves vary over time and between populations. It's also possible that birds of paradise and manakins have similar dancing skills, but so far no one carried out a study like this with them.
To see the video: http://www.eurekalert.org/
To read the paper: http://bit.ly/1bsaOKc
Photo credit: Alex Maisey.
http://www.eurekalert.org/
http://www.newscientist.com/
http://www.wired.com/
http://www.livescience.com/
Sunday, June 9, 2013
The
term, ‘living fossil’ was initially coined by Charles Darwin to
describe creatures that existed for several millions of years in the
fossil record, but had changed very little in that time. Famous examples
include the coelacanth and the lungfish. Conventionally, sturgeon are
considered to be included in this group. But a new study shows that when
it comes to change in body size over time, sturgeon have actually been evolving faster than most other fish.
The study, which was published in Nature Communications, shows that
sturgeons have evolved a huge variety of sizes, from dwarf sturgeon the
size of a bass and some species that can be as big as a car. This is
just one result obtained in the study, which looked into the rate of
species formation and anatomical variation in fish. To do so, an
evolutionary tree linking 7,864 species of fish was assembled. The tree
graphed DNA sequence data and body-size information for each species.
The researchers actually had to develop brand new programs to process
the huge data sets!
Using the raw data and the computer
programs, the researchers studied ‘the correlation between how quickly
new species form and how rapidly they evolve new body sizes’. Sure
enough, a strong correlation was found between species variation and
body size evolution across ray-finned fish. Up till now, the evidence
for this was largely anecdotal. So, while palaeontologists noticed that
groups of organisms with more species tended to have greater anatomical
variation, the theory was never rigorously tested.
The fish can
mostly be organized into two groups. The first group of fish, which
includes the gar, forms species very slowly and has very little
variation in body size. The other group, which includes salmon and
trout, has fast species formation and a large range of body sizes.
In the words of the lead author, "We're basically validating a lot of
ideas that have been out there since Darwin, but which had never been
tested at this scale due to lack of data and the limits of existing
technologies."
But you’re forgetting the sturgeon! The sturgeon
is anomalous in that it does not conform to the general pattern. So,
even though there are only 29 species worldwide, their body size is
highly varied. Pfft… Hipsters!
Read all about it: http://bit.ly/13JKWXt
Image URL: http://bit.ly/11nblY5
The
term, ‘living fossil’ was initially coined by Charles Darwin to
describe creatures that existed for several millions of years in the
fossil record, but had changed very little in that time. Famous examples
include the coelacanth and the lungfish. Conventionally, sturgeon are
considered to be included in this group. But a new study shows that when
it comes to change in body size over time, sturgeon have actually been evolving faster than most other fish.
The study, which was published in Nature Communications, shows that sturgeons have evolved a huge variety of sizes, from dwarf sturgeon the size of a bass and some species that can be as big as a car. This is just one result obtained in the study, which looked into the rate of species formation and anatomical variation in fish. To do so, an evolutionary tree linking 7,864 species of fish was assembled. The tree graphed DNA sequence data and body-size information for each species. The researchers actually had to develop brand new programs to process the huge data sets!
Using the raw data and the computer programs, the researchers studied ‘the correlation between how quickly new species form and how rapidly they evolve new body sizes’. Sure enough, a strong correlation was found between species variation and body size evolution across ray-finned fish. Up till now, the evidence for this was largely anecdotal. So, while palaeontologists noticed that groups of organisms with more species tended to have greater anatomical variation, the theory was never rigorously tested.
The fish can mostly be organized into two groups. The first group of fish, which includes the gar, forms species very slowly and has very little variation in body size. The other group, which includes salmon and trout, has fast species formation and a large range of body sizes.
In the words of the lead author, "We're basically validating a lot of ideas that have been out there since Darwin, but which had never been tested at this scale due to lack of data and the limits of existing technologies."
But you’re forgetting the sturgeon! The sturgeon is anomalous in that it does not conform to the general pattern. So, even though there are only 29 species worldwide, their body size is highly varied. Pfft… Hipsters!
Read all about it: http://bit.ly/13JKWXt
Image URL: http://bit.ly/11nblY5
The study, which was published in Nature Communications, shows that sturgeons have evolved a huge variety of sizes, from dwarf sturgeon the size of a bass and some species that can be as big as a car. This is just one result obtained in the study, which looked into the rate of species formation and anatomical variation in fish. To do so, an evolutionary tree linking 7,864 species of fish was assembled. The tree graphed DNA sequence data and body-size information for each species. The researchers actually had to develop brand new programs to process the huge data sets!
Using the raw data and the computer programs, the researchers studied ‘the correlation between how quickly new species form and how rapidly they evolve new body sizes’. Sure enough, a strong correlation was found between species variation and body size evolution across ray-finned fish. Up till now, the evidence for this was largely anecdotal. So, while palaeontologists noticed that groups of organisms with more species tended to have greater anatomical variation, the theory was never rigorously tested.
The fish can mostly be organized into two groups. The first group of fish, which includes the gar, forms species very slowly and has very little variation in body size. The other group, which includes salmon and trout, has fast species formation and a large range of body sizes.
In the words of the lead author, "We're basically validating a lot of ideas that have been out there since Darwin, but which had never been tested at this scale due to lack of data and the limits of existing technologies."
But you’re forgetting the sturgeon! The sturgeon is anomalous in that it does not conform to the general pattern. So, even though there are only 29 species worldwide, their body size is highly varied. Pfft… Hipsters!
Read all about it: http://bit.ly/13JKWXt
Image URL: http://bit.ly/11nblY5
Friday, June 7, 2013
For prairie voles, love is just a matter of gene switches.
Prairie voles (Microtus ochrogaster) have long drawn the attention of
neuroscientists due to their monogamous lifestyle. Once a pair of
prairie voles mate, they will remain together for the rest of their
lives. But what is the mechanism behind this pair-bond?
Previous studies with these voles implicated two neurotransmitters, vasopressin
and oxytocin. Mated voles are known to have more receptors for these
neurotransmitters than voles who haven't yet mated, and if montane voles
(typically a promiscuous species) receive doses of these
neurotransmitters they too become monogamous.
This study
looked for an epigenetic cause, investigating how mating behaviour
changed gene expression (turning them on or off). The team (of Florida
State University, Tallahassee) administered a drug to prairie voles that
had cohabited for 6 hours but had not mated. This drug blocked a
particular enzyme's activity and allowed the genes for vasopressin and
oxytocin receptors to be "read".
The results were striking.
Though they had not mated, the voles still formed a pair-bond equivalent
to if they had. When compared with the brains of mated voles, the
brains of cohabited voles showed a similar increase in the number of
oxytocin and vasopressin receptors. The drug had created the same
changes as mating.
But the drug alone doesn't cause the
changes: the voles need the 6 hours together too. Social factors are
still very important in creating pair-bonds. This is the first paper
demonstrating epigenetic changes underlying these pair-bonds, but the
researchers believe they've only touched the tip of the iceberg. The
team hope this kind research may lead to a better understanding on
epigenetic changes in humans, particularly those brought about by social
interactions.
Photo credit: Zuoxin Wang.
http://www.nature.com/news/ gene-switches-make-prairie-vole s-fall-in-love-1.13112
http://www.the-scientist.com/ ?articles.view%2FarticleNo%2F35 826%2Ftitle%2FEpigenetics-Play -Cupid-for-Prairie-Voles%2F
Prairie voles (Microtus ochrogaster) have long drawn the attention of neuroscientists due to their monogamous lifestyle. Once a pair of prairie voles mate, they will remain together for the rest of their lives. But what is the mechanism behind this pair-bond?
Previous studies with these voles implicated two neurotransmitters, vasopressin and oxytocin. Mated voles are known to have more receptors for these neurotransmitters than voles who haven't yet mated, and if montane voles (typically a promiscuous species) receive doses of these neurotransmitters they too become monogamous.
This study looked for an epigenetic cause, investigating how mating behaviour changed gene expression (turning them on or off). The team (of Florida State University, Tallahassee) administered a drug to prairie voles that had cohabited for 6 hours but had not mated. This drug blocked a particular enzyme's activity and allowed the genes for vasopressin and oxytocin receptors to be "read".
The results were striking. Though they had not mated, the voles still formed a pair-bond equivalent to if they had. When compared with the brains of mated voles, the brains of cohabited voles showed a similar increase in the number of oxytocin and vasopressin receptors. The drug had created the same changes as mating.
But the drug alone doesn't cause the changes: the voles need the 6 hours together too. Social factors are still very important in creating pair-bonds. This is the first paper demonstrating epigenetic changes underlying these pair-bonds, but the researchers believe they've only touched the tip of the iceberg. The team hope this kind research may lead to a better understanding on epigenetic changes in humans, particularly those brought about by social interactions.
Photo credit: Zuoxin Wang.
http://www.nature.com/news/
http://www.the-scientist.com/
Want
to get involved in some science? The Wildlife Conservation Society
wants you to help them track the 17-years-in-the-making emergence of
cicadas.
After spending 17 years underground, periodical cicada
nymphs emerge for a few short weeks of molting, mating and dying. After
this emergence we won't see this brood again until 2030. If you take a
photo of cicadas on Instagram, geo-tag the photo with
the hashtag #cicadasinmyhood. The WSC plans to collect and compile all
these photos to form an interactive map on its website, http://www.wcs.org/cicadas/.
For those who don't use Instagram, you can help the WCS in other ways.
You can report sightings at magicicada.org. Another project, Urban Buzz,
is looking to receive cicada samples to track body irregularities. Get
involved in documenting this brood's emergence!
http://e.wcs.org/site/ MessageViewer?em_id=31461.0&dlv _id=42241
Photo credit: Medford Taylor.
http://www.livescience.com/ 37239-cicadas-surface-on-instag ram.html
Want
to get involved in some science? The Wildlife Conservation Society
wants you to help them track the 17-years-in-the-making emergence of
cicadas.
After spending 17 years underground, periodical cicada nymphs emerge for a few short weeks of molting, mating and dying. After this emergence we won't see this brood again until 2030. If you take a photo of cicadas on Instagram, geo-tag the photo with the hashtag #cicadasinmyhood. The WSC plans to collect and compile all these photos to form an interactive map on its website, http://www.wcs.org/cicadas/.
For those who don't use Instagram, you can help the WCS in other ways. You can report sightings at magicicada.org. Another project, Urban Buzz, is looking to receive cicada samples to track body irregularities. Get involved in documenting this brood's emergence!
http://e.wcs.org/site/ MessageViewer?em_id=31461.0&dlv _id=42241
Photo credit: Medford Taylor.
http://www.livescience.com/ 37239-cicadas-surface-on-instag ram.html
After spending 17 years underground, periodical cicada nymphs emerge for a few short weeks of molting, mating and dying. After this emergence we won't see this brood again until 2030. If you take a photo of cicadas on Instagram, geo-tag the photo with the hashtag #cicadasinmyhood. The WSC plans to collect and compile all these photos to form an interactive map on its website, http://www.wcs.org/cicadas/.
For those who don't use Instagram, you can help the WCS in other ways. You can report sightings at magicicada.org. Another project, Urban Buzz, is looking to receive cicada samples to track body irregularities. Get involved in documenting this brood's emergence!
http://e.wcs.org/site/
Photo credit: Medford Taylor.
http://www.livescience.com/
Thursday, June 6, 2013
The
human placenta is a confounding organ. Made up almost entirely of
tissue from the fetus, not the mother, the placenta should be attacked
as a foreign invader by the mother’s immune system. And yet, the
placenta makes a nine month pregnancy possible. How?
First, a description of the human placenta:
About four to five days after fertilization, the embryo is a hollow ball of about 100 cells (blastocyst).
Inside and attached to the hollow ball is a group of cells that will
eventually become the fetus, while the outer ball of cells (trophoblast)
will attach to the lining of the uterus and become the placenta. The
attachment is as close as any two human beings will ever be. Once
attached, the trophoblast will actually reroute the mother’s blood
supply to feed the fetus, via the umbilical cord. By the time the baby
is born, the “interface” between mother and placenta is about 12 square
meters.
So how does the placenta keep the mother’s immune
system at bay? Researchers found that the placenta releases exosomes:
small packages packed with information telling the mother’s immune
system to back off. Ian Sargent, a reproductive immunologist at the
University of Oxford in England, describes human reproduction: “It’s
hijacked the immune system and used it for its own purposes.”
After birth, the placenta is expelled from the mother’s body and the
umbilical cord is cut, thus ending the physical connection between
mother and child. Controversy over what to do with the placenta after
birth (some people think it’s a good idea to eat it) has recently
resurfaced in the media. Regardless of what happens to it after those
nine months, the placenta is an amazing organ.
Picture courtesy of:
http://www.sciencephoto.com/ media/478924/view
Sources:
http://www.sciencenews.org/ view/feature/id/350741/ description/Life_Support
The
human placenta is a confounding organ. Made up almost entirely of
tissue from the fetus, not the mother, the placenta should be attacked
as a foreign invader by the mother’s immune system. And yet, the
placenta makes a nine month pregnancy possible. How?
First, a description of the human placenta:
About four to five days after fertilization, the embryo is a hollow ball of about 100 cells (blastocyst). Inside and attached to the hollow ball is a group of cells that will eventually become the fetus, while the outer ball of cells (trophoblast) will attach to the lining of the uterus and become the placenta. The attachment is as close as any two human beings will ever be. Once attached, the trophoblast will actually reroute the mother’s blood supply to feed the fetus, via the umbilical cord. By the time the baby is born, the “interface” between mother and placenta is about 12 square meters.
So how does the placenta keep the mother’s immune system at bay? Researchers found that the placenta releases exosomes: small packages packed with information telling the mother’s immune system to back off. Ian Sargent, a reproductive immunologist at the University of Oxford in England, describes human reproduction: “It’s hijacked the immune system and used it for its own purposes.”
After birth, the placenta is expelled from the mother’s body and the umbilical cord is cut, thus ending the physical connection between mother and child. Controversy over what to do with the placenta after birth (some people think it’s a good idea to eat it) has recently resurfaced in the media. Regardless of what happens to it after those nine months, the placenta is an amazing organ.
Picture courtesy of:
http://www.sciencephoto.com/ media/478924/view
Sources:
http://www.sciencenews.org/ view/feature/id/350741/ description/Life_Support
First, a description of the human placenta:
About four to five days after fertilization, the embryo is a hollow ball of about 100 cells (blastocyst). Inside and attached to the hollow ball is a group of cells that will eventually become the fetus, while the outer ball of cells (trophoblast) will attach to the lining of the uterus and become the placenta. The attachment is as close as any two human beings will ever be. Once attached, the trophoblast will actually reroute the mother’s blood supply to feed the fetus, via the umbilical cord. By the time the baby is born, the “interface” between mother and placenta is about 12 square meters.
So how does the placenta keep the mother’s immune system at bay? Researchers found that the placenta releases exosomes: small packages packed with information telling the mother’s immune system to back off. Ian Sargent, a reproductive immunologist at the University of Oxford in England, describes human reproduction: “It’s hijacked the immune system and used it for its own purposes.”
After birth, the placenta is expelled from the mother’s body and the umbilical cord is cut, thus ending the physical connection between mother and child. Controversy over what to do with the placenta after birth (some people think it’s a good idea to eat it) has recently resurfaced in the media. Regardless of what happens to it after those nine months, the placenta is an amazing organ.
Picture courtesy of:
http://www.sciencephoto.com/
Sources:
http://www.sciencenews.org/
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